Associate Scientist - Drug Metabolism (ADME)

Associate Scientist - Drug Metabolism (ADME) Are you a recent bioscience graduate wanting to contribute to global drug discovery? If so, then this could be the opportunity for you! Role: Associate Scientist - Drug Metabolism (ADME), Permanent Direct Report: to Senior Scientist, Drug Metabolism Hours: Full time, 37.5 hours per week Salary: Starting from £26,000 pa, dependent on skills and experience, with excellent benefits package plus annual bonuses Location: Alderley Park, Macclesfield, SK10 4TG. Our Company Cyprotex vision is to be pioneers of innovative ADME-Tox partnerships, driving delivery of safer and more effective medicines. With state-of-the-art facilities and technical expertise, we specialise in in vitro and in silico ADME-Tox services, providing a wide range of assays tailored to our client’s needs. This includes in vitro screening to support discovery projects, regulatory studies to support preclinical and clinical development, specialist mechanistic in vitro human and animal toxicity models and PBPK/QSAR modelling expertise. As well as supporting clients directly, we have a strong focus on R&D. Our Alderley Park site is set in the heart of Cheshire surrounded by stunning 400-acre estate, open green spaces, sweeping viewpoints, all within easy reach of Merseyside and Greater Manchester, Staffordshire, and Shropshire. Easy access to public transport. As a result of year-on-year success within the company and continued business growth, exciting opportunities have arisen to join our team of 30+ drug metabolism scientists. We are responsible for delivering high quality metabolic stability, enzyme inhibition, enzyme kinetics and enzyme induction data to our clients, supporting projects from early discovery right through to clinical development. As a member of the team you will develop in depth technical expertise across all these areas and understand how this data is utilised to support drug discovery and inform clinical development. Role As an integral member of the Drug Metabolism team, you will work closely with other laboratory staff to ensure that all in vitro drug metabolism studies are performed to a high standard and within scheduled time frames. Key Responsibilities

• Assist in running and maintaining robotic systems to support high throughput ADMET processes
• Assist in data analysis and interpretation by applying scientific knowledge
• Monitor and maintain compounds, stock solutions and buffers.
• Routine calibration of laboratory equipment.
• Follow safety regulations and quality control procedures.
• Able to use initiative to solve problems and troubleshoot, with the assistance of other members of the team.
• Work autonomously as part of the team to deliver team’s priorities, with good organisation and strong communication skills
• Assist senior team members in assay development, validation and bespoke assays, driving forward personal scientific understanding and development

Education, Qualifications and Experience

• Minimum of BSc in a life science subject preferably with experience of working within a laboratory environment (such as a placement year or extended research project).
• Direct experience in DMPK or ADMET assays or working with automated liquid-handling and robotics systems would also be advantageous.
• Previous experience of laboratory processes and cell culture techniques would be desirable.
• Knowledge of HPLC, LC-MS or LC-MS/MS advantageous but not essential.
• Highly self-motivated and personable.
• Able to communicate effectively within a team environment.
• Able to organise daily tasks, to frequently work under pressure and to meet tight deadlines.
• Possess excellent attention to detail, performing work to an exceptionally high standard, and within company and statutory safety regulations.
• Able to use initiative to solve problems and troubleshoot with the assistance of other members of the team.
• Should be computer literate with previous experience using Microsoft Office

What we can offer you in return We offer a competitive salary and benefits package

• Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution and the employer will match the increase up to a maximum of 7.5%.
  • 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days
  • Private health insurance with BUPA for the employee and their partner/family under the company scheme
  • Wellbeing support 24/7 and counselling services
  • Permanent health insurance provides 75% of the base salary after the qualifying period
• Private dental cover, on completion (but not subject to) of your 3-month probationary period
  • Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit.
  • Career progression within the company, we have excellent training and support and continuing professional development opportunities
  • Cycle-to-work scheme
  • Refer a friend scheme, team and annual events, recognition awards and many more!

Onsite Facilities

• The company pays for secure onsite parking
• Restaurant, café, and a gastro pub
• Gym and workout studio, running, walking, and cycling routes
• Good public transport links with the shuttle bus service.

Interested? Apply NOW – please upload your up-to-date CV and cover letter to Workday via our careers page Careers - Cyprotex Closing Date:. FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap. ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.