Senior Scientist, Analytical R&D

Why Patients Need You Here at Pfizer we have a specific purpose – to find breakthroughs that change patients' lives. We are a patient-centric company, guided by our four values: courage, joy, equity and excellence. Our Analytical Research and Development function (ARD) plays a critical role in transforming patients’ lives around the world by supporting the research, development, and manufacture of medicines for studies at all phases of clinical development. As part of Pharmaceutical Sciences in Worldwide R&D, we deliver manufacturing processes that support clinical trials, and help to bring new medicines to market quickly. ARD is responsible for the development and integration of process analytical technology to produce drug products in both continuous and batch processes. What You Will Achieve You will apply your knowledge of Process Analytical Technology (PAT), analytical sciences and machine learning and/or chemometrics to the development of Pfizer’s small molecule R&D portfolio. As a PAT specialist, you will be in the centre of a multi-disciplinary team involving analysts, formulators, process modellers, and chemical engineers from across Pfizer R&D and manufacturing organisations. You will play a key role in the implementation of Pfizer’s strategy to deliver continuous development and manufacturing approaches for investigational new drugs. You’ll be operating in a fast-paced environment, and your personal journey will be actively supported, to help you grow as a leader. Whether you choose to develop as an expert in a specific area, to extend your influence into related scientific and technical disciplines, or to take a business-oriented route into the wider Pfizer family outside of Pharmaceutical Science, you’ll find a workplace culture that helps you to develop and fulfil your aspirations. How You Will Achieve It You will

• Develop, design, and perform experiments related to Process Analytical Technology methods to support the development of batch and continuous drug product processes.
• Interact seamlessly with subject matter experts, and partner with formulators, analysts, process modellers and chemical engineers from across Pfizer R&D and manufacturing organizations as part of a multi-disciplinary project team.
• Help to establish the effective operation of a new GMP continuous manufacturing facility.
• Work in a global organisation, by interacting with counterparts at different locations working on similar platforms and systems.
• Support the application of new and existing PAT methodologies to enable the development and transfer of processes to GMP manufacturing facilities.
• Develop automated data analysis solutions for continuous and batch manufacturing platforms.
• Mentor and collaborate with peers.
• Interact with, and present effectively to management and senior management.
• Engage with the external scientific community through publications and presentations.
• Apply PAT methodologies to support the validation of existing and novel continuous drug product manufacturing platforms.

Qualifications Must-Have

• BSc or MSc degree in a STEM subject
• Proven extensive experience in a relevant industrial or research setting.
• Excellent communication and personal interaction skills
• Knowledge of at least one vibrational spectroscopy area (NIR, mid-IR, Raman, UV/Vis) with hands-on experience in the integration of process analytics to quantify solid or liquid samples.
• Comfortable using advanced data searching and visualisation tools, and self-assured in deploying data modelling and simulation packages.
• Able to readily utilise at least one of: MATLAB, Python, PharmaMV or DeltaV.
• Conversant with data collection and analysis, including chemometrics, and statistical approaches and principles.

Nice-to-Have

• Ph.D. in Pharmaceutical Sciences, Chemistry, or Chemical Engineering
• PAT experience with small molecule manufacturing processes.
• Knowledge of general analytical techniques and instrumentation.
• An understanding of the differences between pharmaceutical R&D and commercial manufacturing environments.
• Experience with Process Analytical Technology (PAT) method development, validation and implementation.
• Experience in continuous manufacturing or process control in pharmaceuticals, fine chemicals, or related industries.

Flexible working We aim to create a trusting, flexible workplace culturewhich encourages employees to achieve work life harmony, attracts talent and enables everyone to be their best working self. Let’s start the conversation! Employee Equal Opportunities We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees.

Work Location Assignment: On Premise Purpose Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives. Digital Transformation Strategy One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience. Flexibility We aim to create a trusting, flexible workplace culture which encourages employees to achieve work life harmony, attracts talent and enables everyone to be their best working self. Let’s start the conversation! Equal Employment Opportunity We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. DisAbility Confident We are proud to be a Disability Confident Employer and we encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments necessary to support your application and future career. Our mission is unleashing the power of our people, especially those with unique superpowers. Your journey with Pfizer starts here! Research and Development